Stress granules (SG) and processing bodies (PB) in viral infections
Magdalena Malinowska, Paulina Niedźwiedzka-Rystwej, Beata Tokarz-Deptuła and Wiesław Deptuła
Keyword: stress granules, processing bodies, viral infection
During reaction to stress caused by viral infection, RNA granules are formed in order to protect mRNA. Stress granules (SG) and processing bodies (PB) provide cell homeostasis and mRNA stability. They are formed, for example, during polio virus and MRV (mammalian orthoreovirus) infections. Some viruses, such as influenza virus and HTLV-1 (Human T-lymphotropic virus 1), block the formation of granules. In addition, there are viruses like West Nile Virus, Hepatitis C Virus (HCV) or human Herpes viruses, which influence the functioning of the granules.
Acta Biochimica Polonica, 63(2), 183-188, Review, DOI: 10.18388/abp.2015_1060
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